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Enclomiphene citrate is the trans isomer of clomiphene citrate and acts for a non-steroidal estrogen receptor antagonist.

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Currently being a SERM, Citrate has the opportunity to bind with estrogen receptors within the investigation topics. Just after binding, it may well stop estrogen manufacturing and signal the brain to provide testosterone. This signaling could produce an increase in testosterone concentrations inside the topics. 

Enclomiphene citrate has become the subject of various clinical research, especially focusing on its power to elevate serum testosterone stages although preserving typical sperm counts in male subjects with secondary hypogonadism.